|
Abstract
Plasmid pLD105 isolated from a clinical strain of E. coli determines nitrofuran resistance due to
inactivation of low-molecular-weight nitrofuran reductase subunit. pLD105 plasmid belongs to IncF.
It is a conjugative plasmid and mobilizes chromosome markers, but is not transmitted to strains
containing other plasmids. However, the presence of pLD105 plasmid in the recipient strain does
not prevent incorporation of other plasmids, including nonconjugative ones. Transfer of nonconjugative
plasmids from the donor to a recipient strain carrying pLD105 was denoted as "reverse donation". |