Shemiakin I.G., Stepanshina V.N., Korobova O.V., Anisimova V.A., Ivanov I.Iu., Lipin M.Iu., Lazarev A.A., Skaldina A.I., Chernavskaia L.A., Tarasova T.I.

[Genetic typing of Mycobacterium tuberculosis strains by spoligotyping and genome fingerprinting techniques]

Zh Mikrobiol Epidemiol Immunobiol. 2002 Nov-Dec;(6):30-5.

Abstract
A total of 122 M. tuberculosis clinical drug-resistant strains isolated in Central Russia were studied by spoligotyping and genome fingerprinting techniques. According to spoligotyping results 77% of M. tuberculosis strains were distributed to 13 oligotypes, while 23% of these strains were found to form unique patterns. Most of them belonged to the families Beijing and Haarlem (43.4% and 13.9% respectively). The patterns of the strains of oligotype 12 (7F-7F-7E-0E-78-3E) were identical to those of the strains isolated in Brazil, France and the Netherlands. The strains of the spoligotype 22 (7F-1E-7F-7F-07-3E) had the patterns identical to those of the strains of group S13, also isolated in Brazil. According to genome fingerprinting 31.4% of the strains were found to belong to clusters with the similarity coefficient equal to 1. The strains belonging to genotypes W and A1 were found to prevail in the analyzed group.

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Публикации 2002 г.